DeNovix – Spectrophotometer UV-Vis

DS-11 Series Spectrophotometer / Fluorometer

DeNovix takes spectrophotometry to a whole new level of performance with the DS-11 Series. This easy-to-use, compact instrument delivers full spectrum UV-Vis analysis and fluorescence capability making it ideal for rapid nucleic acid and protein quantification. Our customers agree and have made the DeNovix DS-11 Series the twice winner of the Reviewers’ Choice Product of the Year and the first life science instrument to be awarded the Platinum Seal of Quality by SelectScience based on scientist reviews for outstanding ease-of-use, performance, service and technical support. Best in Class 1 uL Sensitivity and Highest Absorbance Capability. The Only All-In-One Microvolume and Cuvette Absorbance with Fluorescence Design.

 

Multiple Model and Color Choices

The DS-11 Series is available in 4 models with different combinations of microvolume absorbance (M), cuvette absorbance (C) and Fluorescence (F):

• DS-11 FX+ (M/C/F)
• DS-11 FX (M/F)
• DS-11+ (M/C)
• DS-11 (M)

INTEGRATED ABSORBANCE AND FLUORESCENCE FOR UNMATCHED FLEXIBILITY

The Only All-In-One Microvolume and Cuvette Absorbance with Fluorescence Design

With the DS-11 Series you can equip your lab for today’s quantification requirements and for future assay challenges. Combine the ease of use, wide dynamic range and contamination information of UV-Vis with the enhanced sensitivity and specific quantification of fluorescence for total sample quality control.

Absorbance and Fluorescence quantification are unique but complementary methods for assessing the concentration and quality of biological samples. The multi-award winning DS-11 Series of 1 µL Spectrophotometers and Fluorometers provides the most sensitive and widest dynamic range for UV-Vis absorbance and fluorescence capability in one combined instrument.

1. Sensitivity – Extend the lower detection limit for low-concentration samples. Quantify down to 0.5 pg/µL dsDNA
2. Specificity – Selectively quantify your sample in the presence of contaminants using DeNovix Fluorescence Quantification Assays
3. Total Sample QC – Combine Absorbance and Fluorescence measurements for specific quantification and reliable contamination detection.

 

21 CFR Part 11 Compliance Ready

EasyApps Secure provides an optional suite of software controls that allow regulated GxP facilities to easily add DS-11 Series instruments to their compliant workflows (view the compliance statement). The software is fully integrated within the on-board operating system and includes a range of features essential to ensuring compliance, including:

• Password-protected system access
• Integrated electronic signature controls
• Comprehensive user account management
• Secure audit trail recording
• Advanced data handling and export tools

 

FX Module: Upgrade to Fluorescence

Instantly add the power of fluorescence detection to any DeNovix DS-11, DS-11+ or DS-C Spectrophotometer. The FX Module uses the same fluorescence detection as the DS-11 FX, DS-11 FX+ and QFX. Simply plug in this USB powered accessory and DeNovix fluorometric EasyApps are immediately enabled. With four user-selectable LEDs, the easy-to-use apps are compatible with a wide range of commercially available assays including those designed for Thermo Fisher’s Qubit™ fluorometer and Promega’s Quantus™ fluorometer platforms.

 

Absorbance and Fluorescence Quantification Infographic

Absorbance and Fluorescence quantification are unique but complementary methods for assessing concentration and quality of biological samples. The multi-award winning DS-11 Series of 1 µL Spectrophotometers and Fluorometers provides the most sensitive and widest dynamic range for UV-Vis absorbance and fluorescence capability in one combined instrument.

Selecting the appropriate quantification methods for biological samples is an important consideration in any quality control process. Download our infographic featuring comparisons of the key features of absorbance and fluorescence quantification and information on when each method should be applied or the results combined.

 

Download Infographic

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Helium 1 µL Spectrophotometer

DeNovix takes spectrophotometry to a whole new level of performance with the Helium 1 µL Spectrophotometer. This easy-to-use, compact instrument delivers rapid nucleic acid and protein quantification, making it ideal for both research and teaching labs. Backed by world-renowned DeNovix reliability and support, the Helium Spectrophotometer offers unparalleled value for money.

Affordable, Reliable Quantification

The Helium Microvolume Spectrophotometer enables easy biomolecule quantification in under 5 seconds with as little as 1 µL of sample. This efficiency reduces sample waste and operational costs, making it a cost-effective solution for labs of all sizes. The instrument is ideal for the analysis of nucleic acids and proteins using absorbance measurements at 260 nm, 280 nm, and 230 nm. Its affordability does not compromise on reliability, ensuring consistent and accurate results across various applications in biotechnology, pharmaceuticals, environmental science, clinical diagnostics, and education.

Powerful EasyApps™ Software

• Quantify dsDNA, ssDNA, RNA, and Protein.
• Assess sample quality with built-in purity ratios (260/230 and 260/280).
• No setup needed.
• Easily review and export results to USB or label printer.
• Store up to 2,000 samples.
• Maintenance-free design ensures lifetime consistency with no recalibration needed.

Proven DeNovix Technology

Helium employs the same core DeNovix technology trusted by thousands of researchers worldwide. SmartPath™ technology combines hardware and software to provide real-time optimization of every sample, ensuring measurement confidence. This technology is particularly beneficial in high-throughput environments such as pharmaceutical labs and clinical diagnostics, where precision and reliability are paramount.

Helium 1 µL Spectrophotometer Advanced Features

• High Sensitivity: Detects low-concentration samples with high accuracy, crucial for applications in genetic research and molecular biology.
• Wide Dynamic Range: Suitable for a variety of sample types and concentrations, making it versatile for environmental testing and quality control in manufacturing.
• Compact Design: Fits easily into any lab space, ideal for both small academic labs and large industrial facilities.
• User-Friendly Interface: Simplifies operation and data management, enhancing productivity in busy lab settings.

The Helium 1 µL Spectrophotometer is designed to meet the high standards of modern laboratories, providing consistent and accurate results every time. With its advanced features and reliable performance, it is an essential tool for any lab focused on nucleic acid and protein quantification.

Helium 1 µL Spectrophotometer User Guide

Helium 1 µL Spectrophotometer Brochure

 

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DS-8X Series Spectrophotometer

The DeNovix DS-8X Series is a stand-alone, eight-channel UV-Vis spectrophotometer designed for high-throughput nucleic acid and protein quantification. With full-spectrum analysis, rapid measurement speed, and advanced SmartQC™ technology, the DS-8X delivers unmatched performance, reliability, and ease of use—ideal for busy molecular biology and genomics labs. Optionally, for added flexibility, the DS-8X+ model offers optional cuvette and fluorescence detection modes, expanding the system’s capabilities to meet evolving assay needs.

DeNovix DS-8X Key Features

• Eight-Channel UV-Vis Spectrophotometry
  Measure up to 8 samples simultaneously in ~10 seconds or a single sample in just 2 seconds.
• SmartPath™ Technology
  Real-time pathlength optimization ensures accurate and reproducible results.
• Bridge Testing™ Verification
  Automatically detects and corrects for broken sample columns or pipetting errors.
• SmartQC™ Sample Assurance
  Includes micron-level pathlength control, continuous sample compression, and anomaly detection algorithms.
• Maintenance-Free Design
  No recalibration required throughout the instrument’s lifetime.
• EasyApps™ Software
  Intuitive, touchscreen-driven software designed specifically for life science workflows.
• 21 CFR Part 11 Compliance Ready
  Optional EasyApps Secure software includes audit trails, electronic signatures, and user access controls.
• Stand-Alone Operation
  7” HD touchscreen with glove compatibility—no PC required.
• LED Sample Tracker
  Optional USB accessory with software-controlled LEDs for guided sample loading.
• Color Options
  Available in Brazilian Blue, Arctic White, Tungsten Silver, and Fire Red.

Technical Specifications

• Wavelength Range: 190–840 nm
• Sample Volume: 1 µL
• Detection Range (dsDNA): 2–11,000 ng/µL
• Measurement Time: ~2 sec (single), ~10 sec (eight samples)
• Modes: UV-Vis (standard), Cuvette and Fluorescence (optional with DS-8X+)
• Compliance: 21 CFR Part 11 (with EasyApps Secure)
• Connectivity: USB, LIMS-compatible export
• Software: EasyApps with AutoRun, Purity Ratio Alerts, and CSV import/export

Applications

• Nucleic Acid Quantification (dsDNA, RNA, ssDNA, Microarray)
• Protein Quantification
• UV-Vis Absorbance
• Custom Kinetics / OD600
• Fluorescence (with FX Module)

Optional Accessories

• FX Fluorescence Module – Plug-and-play USB accessory for fluorescence quantification
• Cuvette Mode – Extend detection limits with optional cuvette capability (DS-8X+)
• LED Sample Tracker – Software-guided sample loading with illuminated columns

Compliance & Workflow Integration

• EasyApps Secure: Enables 21 CFR Part 11 compliance
• IQ/OQ Documentation: Available for regulated environments
• LIMS-Compatible: Flexible import/export for seamless data integration

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