DeNovix

CellDrop FLxi Automated Cell Counter

The DeNovix CellDrop FLxi is engineered for advanced fluorescence-based cell counting, offering high-resolution imaging and enhanced sensitivity for small, irregular, or clustered cells. Featuring a 10X objective, the FLxi is ideal for applications involving organoids, yeast, fixed nuclei, and other challenging sample types. Like all CellDrop models, it utilizes DeNovix’s DirectPipette™ technology, allowing users to count cells without disposable slides—saving time, reducing plastic waste, and simplifying workflows. With machine learning-powered image analysis, customizable protocols, and rapid results, the FLxi delivers precision and performance for researchers who demand more from their cell counting instrumentation.

CellDrop FLxi Key Features

• Dual Fluorescence + Brightfield Imaging
  Optimized for small and complex samples.
• 10X Objective
  Supports cell sizes from 2–20 µm with enhanced resolution.
• DirectPipette™ Technology
  Count cells without slides using a wipe-clean, variable-height chamber.
• Measurement Modes
  Supports DirectPipette™, reusable slides, and single-use plastic slides.
• Machine Learning-Based Apps
  Advanced image analysis for irregular and clustered cells.
• EasyApps™ Software
  Includes gating, declustering, custom protocols, and graphical data display.
• Fast, Accurate Results
  Total, live, dead cell counts and viability in seconds.
• Connectivity
  Wi-Fi, USB, Ethernet, and email for flexible data export.
• Color Options
  Available in Arctic White and Leaf Green.

Applications

• Organoids
• Yeast
• GFP Transfection
• Fixed Nuclei
• Algae
• Insect Cells
• Protoplasts
• Small Cell Populations

Compliance & Workflow Integration

• 21 CFR Part 11 Ready
  EasyApps Secure software supports regulated workflows.
• Hazardous Sample Compatibility
  Compatible with disposable and reusable slides for containment.

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CellDrop Cell Counters

Mason Technology in partnership with DeNovix are delighted to bring our customers the DeNovix CellDrop Automated Cell Counter series. The DeNovix CellDrop Automated series feature patented DirectPipette™ Technology to eliminate plastic slides and cumbersome hemocytometers from routine cell counting. DeNovix CellDrop Automated Cell Counters feature dual fluorescence and brightfield optics, variable height sample chamber, and powerful, easy-to-use analysis software. The instruments enable the fastest cell counts, viability assessment, and GFP transfection efficiency measurements across the widest range of cell density, cell type and application.

The DeNovix CellDrop is rated five stars by scientists worldwide and was awarded Best New Life Science Product of the Year!

Key benefits of the DeNovix CellDrop:

• DirectPipette™ Technology: The CellDrop Automated Cell Counter Series brings the familiar Load, Measure & Wipe Clean functionality of microvolume spectrophotometers to cell counting. Traditional plastic slides or glass hemocytometers are replaced by two permanent optical sapphire surfaces. These are positioned parallel to one another by a calibration-free, high-precision mechanism, forming a chamber of precisely defined height. 10µL of cell suspension is pipetted into the chamber, analyzed and simply wiped away with a dry laboratory wipe. The powerful live-view image allows instant verification that cleaning has been successful.
• Accurate Across the Widest Range of Cell Size and Density: Using conventional counting methods, samples with high or low cell densities require time consuming dilution or concentration steps. The variable height chamber of the CellDrop Automated Cell Counters enables the most accurate counts over the widest cell densities – 7 x 10² – 2.5 x 10⁷. Chamber height can also be adjusted to accommodate almost any cell with a diameter range of 4 to 400µm.
• Easy to Learn. Powerful to Use: Designed by life scientists, the CellDrop EasyApps^® Software exceeds the functionality of high cost cell counters while also delivering the ease-of-use of simpler systems. EasyApps and the high definition, 7″ touchscreen interface provides intuitive cell counting, from sample loading to data exporting in seconds. Pre-installed applications include a range of common applications for one-touch analysis of assays such as Brightfield, Trypan blue, AO/PI, GFP and Yeast and the ability to create custom methods. CellDrop Cell Counters are a flexible workhorse for the busy, multi-user lab.

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DS-11 Series Spectrophotometer / Fluorometer

DeNovix takes spectrophotometry to a whole new level of performance with the DS-11 Series. This easy-to-use, compact instrument delivers full spectrum UV-Vis analysis and fluorescence capability making it ideal for rapid nucleic acid and protein quantification. Our customers agree and have made the DeNovix DS-11 Series the 2017 and 2018 Reviewers’ Choice Product of the Year and the first life science instrument to be awarded the Platinum Seal of Quality by SelectScience based on scientist reviews for outstanding ease-of-use, performance, service and technical support.

This product is provided under an intellectual property license from Life Technologies Corporation – for more information visit www.denovix.com/license/

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QFX Fluorometer

The QFX Fluorometer is more sensitive and reproducible than any other instrument in its class. The QFX is a powerful solution for all fluorometric applications where enhanced specificity or sensitivity are needed. Quantify nucleic acids and proteins using four fluorescent channels with a choice of common assays built into measurement apps or easily create custom apps for the ultimate in fluorometer flexibility. The QFX outperforms Qubit® and other tube fluorometers giving superior data quality, more powerful software and full network integration for seamless data handling.

This product is provided under an intellectual property license from Life Technologies Corporation – for more information visit www.denovix.com/license/

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Denovix Fluorescence Spectroscopy

DeNovix takes spectrophotometry to a whole new level of performance with the DS-11 Series. This easy-to-use, compact instrument delivers full spectrum UV-Vis analysis and fluorescence capability making it ideal for rapid nucleic acid and protein quantification. Our customers agree and have made the DeNovix DS-11 Series the 2017 and 2018 Reviewers’ Choice Product of the Year and the first life science instrument to be awarded the Platinum Seal of Quality by SelectScience based on scientist reviews for outstanding ease-of-use, performance, service and technical support.

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Helium 1 µL Spectrophotometer

DeNovix takes spectrophotometry to a whole new level of performance with the Helium 1 µL Spectrophotometer. This easy-to-use, compact instrument delivers rapid nucleic acid and protein quantification, making it ideal for both research and teaching labs. Backed by world-renowned DeNovix reliability and support, the Helium Spectrophotometer offers unparalleled value for money.

Affordable, Reliable Quantification

The Helium Microvolume Spectrophotometer enables easy biomolecule quantification in under 5 seconds with as little as 1 µL of sample. This efficiency reduces sample waste and operational costs, making it a cost-effective solution for labs of all sizes. The instrument is ideal for the analysis of nucleic acids and proteins using absorbance measurements at 260 nm, 280 nm, and 230 nm. Its affordability does not compromise on reliability, ensuring consistent and accurate results across various applications in biotechnology, pharmaceuticals, environmental science, clinical diagnostics, and education.

Powerful EasyApps™ Software

• Quantify dsDNA, ssDNA, RNA, and Protein.
• Assess sample quality with built-in purity ratios (260/230 and 260/280).
• No setup needed.
• Easily review and export results to USB or label printer.
• Store up to 2,000 samples.
• Maintenance-free design ensures lifetime consistency with no recalibration needed.

Proven DeNovix Technology

Helium employs the same core DeNovix technology trusted by thousands of researchers worldwide. SmartPath™ technology combines hardware and software to provide real-time optimization of every sample, ensuring measurement confidence. This technology is particularly beneficial in high-throughput environments such as pharmaceutical labs and clinical diagnostics, where precision and reliability are paramount.

Helium 1 µL Spectrophotometer Advanced Features

• High Sensitivity: Detects low-concentration samples with high accuracy, crucial for applications in genetic research and molecular biology.
• Wide Dynamic Range: Suitable for a variety of sample types and concentrations, making it versatile for environmental testing and quality control in manufacturing.
• Compact Design: Fits easily into any lab space, ideal for both small academic labs and large industrial facilities.
• User-Friendly Interface: Simplifies operation and data management, enhancing productivity in busy lab settings.

The Helium 1 µL Spectrophotometer is designed to meet the high standards of modern laboratories, providing consistent and accurate results every time. With its advanced features and reliable performance, it is an essential tool for any lab focused on nucleic acid and protein quantification.

Helium 1 µL Spectrophotometer User Guide

Helium 1 µL Spectrophotometer Brochure

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DS-8X Series Spectrophotometer

The DeNovix DS-8X Series is a stand-alone, eight-channel UV-Vis spectrophotometer designed for high-throughput nucleic acid and protein quantification. With full-spectrum analysis, rapid measurement speed, and advanced SmartQC™ technology, the DS-8X delivers unmatched performance, reliability, and ease of use—ideal for busy molecular biology and genomics labs. Optionally, for added flexibility, the DS-8X+ model offers optional cuvette and fluorescence detection modes, expanding the system’s capabilities to meet evolving assay needs.

DeNovix DS-8X Key Features

• Eight-Channel UV-Vis Spectrophotometry
  Measure up to 8 samples simultaneously in ~10 seconds or a single sample in just 2 seconds.
• SmartPath™ Technology
  Real-time pathlength optimization ensures accurate and reproducible results.
• Bridge Testing™ Verification
  Automatically detects and corrects for broken sample columns or pipetting errors.
• SmartQC™ Sample Assurance
  Includes micron-level pathlength control, continuous sample compression, and anomaly detection algorithms.
• Maintenance-Free Design
  No recalibration required throughout the instrument’s lifetime.
• EasyApps™ Software
  Intuitive, touchscreen-driven software designed specifically for life science workflows.
• 21 CFR Part 11 Compliance Ready
  Optional EasyApps Secure software includes audit trails, electronic signatures, and user access controls.
• Stand-Alone Operation
  7” HD touchscreen with glove compatibility—no PC required.
• LED Sample Tracker
  Optional USB accessory with software-controlled LEDs for guided sample loading.
• Color Options
  Available in Brazilian Blue, Arctic White, Tungsten Silver, and Fire Red.

Technical Specifications

• Wavelength Range: 190–840 nm
• Sample Volume: 1 µL
• Detection Range (dsDNA): 2–11,000 ng/µL
• Measurement Time: ~2 sec (single), ~10 sec (eight samples)
• Modes: UV-Vis (standard), Cuvette and Fluorescence (optional with DS-8X+)
• Compliance: 21 CFR Part 11 (with EasyApps Secure)
• Connectivity: USB, LIMS-compatible export
• Software: EasyApps with AutoRun, Purity Ratio Alerts, and CSV import/export

Applications

• Nucleic Acid Quantification (dsDNA, RNA, ssDNA, Microarray)
• Protein Quantification
• UV-Vis Absorbance
• Custom Kinetics / OD600
• Fluorescence (with FX Module)

Optional Accessories

• FX Fluorescence Module – Plug-and-play USB accessory for fluorescence quantification
• Cuvette Mode – Extend detection limits with optional cuvette capability (DS-8X+)
• LED Sample Tracker – Software-guided sample loading with illuminated columns

Compliance & Workflow Integration

• EasyApps Secure: Enables 21 CFR Part 11 compliance
• IQ/OQ Documentation: Available for regulated environments
• LIMS-Compatible: Flexible import/export for seamless data integration

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CellDrop FLi Automated Cell Counter

The DeNovix CellDrop FLi is a powerful, slide-free automated cell counter designed to streamline cell counting workflows in research and clinical laboratories. Combining brightfield and dual fluorescence imaging with DeNovix’s patented DirectPipette™ technology, the FLi eliminates the need for disposable plastic slides, reducing waste and cost while improving convenience. This compact, stand-alone instrument delivers rapid and accurate cell counts, viability assessments, and transfection efficiency measurements—all with minimal sample volume and no calibration required. Whether you’re working with primary cells, tissue culture, or fixed samples, the CellDrop FLi offers unmatched flexibility, precision, and sustainability in a single, easy-to-use platform.

CellDrop FLi Key Features

• Dual Fluorescence + Brightfield Imaging
  Enables precise viability and transfection efficiency measurements.
• DirectPipette™ Technology
  Count cells without slides using a wipe-clean, variable-height chamber.
• 4X Objective
  Ideal for cell sizes ranging from 4–400 µm.
• Measurement Modes
  Supports DirectPipette™, reusable slides, and single-use plastic slides.
• EasyApps™ Software
  Intuitive interface with pre-configured protocols, gating, declustering, and data export.
• Fast Results
  Total, live, dead cell counts and viability in under 10 seconds.
• Connectivity
  Wi-Fi, USB, Ethernet, and email for seamless data sharing.
• Maintenance-Free Design
  No recalibration required for the life of the instrument.
• Color Options
  Available in Arctic White and Leaf Green.

Applications

• Primary Cells
• Tissue Culture
• Yeast
• Algae
• Insect Cells
• Protoplasts
• Fixed Samples
• GFP Transfection Efficiency

Compliance & Workflow Integration

• 21 CFR Part 11 Ready
  Optional EasyApps Secure software includes password protection, audit trails, and electronic signatures.
• Hazardous Sample Compatibility
  Use with disposable or reusable slides inside flow hoods.

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