Service Request Request a Quote

Nanobody Reagents

Mason Technology supplies ChromoTek® Nanobody Based Reagents from Proteintech to research laboratories across Ireland, providing scientists with innovative nanobody technologies that deliver exceptional performance for protein analysis, imaging and purification. Originally developed by ChromoTek and now part of the Proteintech portfolio, these recombinant nanobody based reagents offer significant advantages over conventional antibodies through their small size, high affinity and outstanding specificity. They are trusted by researchers worldwide for applications where sensitivity, reproducibility and image resolution are critical.

Nanobodies, also known as VHH antibodies, are derived from camelid heavy chain only antibodies and represent the smallest naturally occurring antigen binding domains. Their compact structure enables improved tissue penetration, reduced epitope to label distance and lower background compared with traditional IgG antibodies. Recombinantly produced under tightly controlled conditions, ChromoTek nanobody reagents provide excellent batch to batch consistency while supporting reliable and reproducible experimental results. The portfolio includes Nano Traps® for immunoprecipitation, Nano Secondary® reagents, Chromobodies® for live cell imaging, Primary VHH nanobodies, Nano Caps®, Nano CaptureLigands, the Spot Tag® System and other specialist tools designed for modern life science research.

ChromoTek® Nanobody Based Reagents Key Features

Recombinant alpaca derived nanobody VHH technology.
Smaller than conventional antibodies for improved tissue penetration and higher imaging resolution.
High affinity and exceptional target specificity.
Recombinant production for consistent batch to batch performance.
Low background and reduced non-specific binding.
Solutions for immunoprecipitation, immunofluorescence, Western blotting, live cell imaging, protein purification and flow cytometry.
Comprehensive product range including Nano Traps®, Nano Secondary®, Chromobodies®, Primary VHHs and the Spot Tag® System.
Stable under demanding experimental conditions.
Extensive validation data and application support.
Expert technical guidance from Mason Technology.

ChromoTek nanobody based reagents have become indispensable tools for researchers seeking greater sensitivity and reproducibility in protein analysis. Their unique single domain structure reduces steric hindrance, allowing nanobodies to bind targets that may be inaccessible to conventional antibodies. This results in improved immunoprecipitation efficiency, higher resolution fluorescence imaging, cleaner Western blots and more effective protein purification workflows. Researchers working in cell biology, structural biology, neuroscience, immunology and proteomics can benefit from the enhanced performance these innovative reagents provide across a broad range of experimental applications.

As Proteintech’s trusted partner in Ireland, Mason Technology combines access to the complete ChromoTek portfolio with responsive local technical support and product expertise. Our experienced Life Sciences team can help you select the most appropriate nanobody based reagent for your application, whether you require high-performance immunoprecipitation tools, advanced live cell imaging reagents or innovative solutions for protein purification and analysis. Explore the complete ChromoTek range through Mason Technology and discover how nanobody technology can enhance the quality and reproducibility of your research.

FEATURED PRODUCTS

Quick View Enquire Now

Nano-Traps®

Nano-Traps® from ChromoTek, available through Mason Technology, provide researchers with an advanced nanobody-based solution for immunoprecipitation,...

More About Nano-Traps®

Expand Close

Nano-Traps®

Nano-Traps® from ChromoTek, available through Mason Technology, provide researchers with an advanced nanobody-based solution for immunoprecipitation, co-immunoprecipitation and protein interaction studies. Built around recombinant VHH nanobody technology, Nano-Traps® offer exceptional affinity, specificity and reproducibility, allowing laboratories to isolate target proteins efficiently while reducing background binding. Their robust performance has made them a trusted choice for researchers investigating protein complexes, signalling pathways and cellular function.

Unlike conventional antibody-based immunoprecipitation reagents, Nano-Traps® use recombinant alpaca-derived nanobodies that recognise specific protein tags or endogenous proteins with high precision. Their compact size enables improved access to target epitopes while reducing steric hindrance, leading to more efficient protein capture. The recombinant production process also eliminates the batch variability commonly associated with traditional antibodies, providing consistent experimental performance across long-term research projects.

Nano-Traps® are supplied pre-coupled to agarose or magnetic beads, simplifying laboratory workflows and reducing hands-on preparation. They are compatible with a wide range of downstream applications, including Western blotting, mass spectrometry and protein interaction analysis, making them valuable tools for molecular biology, cell biology and proteomics research.

Nano-Traps® Key Features

Recombinant nanobody-based immunoprecipitation reagents.
High affinity and exceptional target specificity.
Pre-coupled to agarose or magnetic beads.
Low background and reduced non-specific binding.
Excellent batch-to-batch consistency.
Compatible with co-immunoprecipitation workflows.
Supports Western blotting, proteomics and mass spectrometry.
Suitable for GFP, RFP, Myc, HA and other tagged proteins.
Rapid and reproducible protein isolation.
Supported by Mason Technology’s technical specialists.

Protein purification and interaction studies require reagents that deliver consistent, high-quality results. Nano-Traps® provide an efficient alternative to traditional antibody-based immunoprecipitation, helping researchers isolate proteins with greater confidence while simplifying experimental workflows. Their outstanding specificity and reproducibility make them ideal for both routine laboratory work and advanced proteomics research.

Mason Technology supplies the complete ChromoTek Nano-Traps® portfolio throughout Ireland, providing local technical support and expert product guidance to help laboratories optimise their protein analysis workflows.

Finding the right products for your research can be overwhelming. Proteintech’s new AI powered search tool, ‘Able’, makes the process easier and faster.

NEED EXPERT ADVICE?

Quick View Enquire Now

Primary VHH Nanobodies

Primary VHH Nanobodies from ChromoTek, available through Mason Technology, offer researchers an innovative alternative to conventional primary antibod...

More About Primary VHH Nanobodies

Expand Close

Primary VHH Nanobodies

Primary VHH Nanobodies from ChromoTek, available through Mason Technology, offer researchers an innovative alternative to conventional primary antibodies for protein detection and imaging. Developed using recombinant camelid single-domain antibody technology, these nanobodies combine exceptional specificity with a molecular size significantly smaller than traditional IgG antibodies. The result is improved tissue penetration, enhanced imaging resolution and highly reproducible performance across a broad range of research applications.

Their compact structure allows Primary VHH Nanobodies to bind epitopes that may be difficult for larger antibodies to access. This makes them particularly valuable for super-resolution microscopy, immunofluorescence, immunohistochemistry and protein localisation studies, where reducing the distance between the target protein and fluorescent label improves image accuracy.

Produced recombinantly under tightly controlled conditions, Primary VHH Nanobodies deliver excellent batch-to-batch consistency and eliminate the variability associated with hybridoma-derived antibodies. Researchers also benefit from lower background staining and improved signal-to-noise ratios, resulting in clearer experimental data and more reliable interpretation.

Primary VHH Nanobodies Key Features

Recombinant alpaca-derived VHH nanobodies.
Significantly smaller than conventional IgG antibodies.
High affinity and excellent target specificity.
Improved tissue penetration and epitope accessibility.
Reduced background staining.
Ideal for immunofluorescence and super-resolution microscopy.
Excellent batch-to-batch consistency.
Recombinant production for reliable reproducibility.
Suitable for multiple protein detection applications.
Supported by Mason Technology.

Primary VHH Nanobodies provide researchers with a modern approach to protein detection by combining high specificity with the unique advantages of recombinant nanobody technology. Their ability to generate high-resolution images and reproducible staining makes them particularly valuable in cell biology, neuroscience and structural biology research.

As Proteintech’s trusted partner in Ireland, Mason Technology provides access to the complete ChromoTek Primary VHH portfolio together with expert technical guidance and responsive customer support.

Finding the right products for your research can be overwhelming. Proteintech’s new AI powered search tool, ‘Able’, makes the process easier and faster.

NEED EXPERT ADVICE?

Quick View Enquire Now

Anti-IgG VHH Beads for Immunoprecipitation

Anti-IgG VHH Beads from ChromoTek, available through Mason Technology, are designed to simplify antibody-based immunoprecipitation by providing highly...

More About Anti-IgG VHH Beads for Immunoprecipitation

Expand Close

Anti-IgG VHH Beads for Immunoprecipitation

Anti-IgG VHH Beads from ChromoTek, available through Mason Technology, are designed to simplify antibody-based immunoprecipitation by providing highly specific capture of IgG antibodies using recombinant nanobody technology. These innovative reagents deliver efficient antibody immobilisation while reducing non-specific binding, enabling researchers to obtain cleaner immunoprecipitation results and improved reproducibility.

Unlike traditional Protein A or Protein G resins, Anti-IgG VHH Beads employ recombinant nanobodies engineered to bind immunoglobulins with exceptional specificity. Their defined binding characteristics reduce variability and improve consistency between experiments, making them ideal for applications requiring dependable protein capture and interaction analysis.

Supplied as ready-to-use magnetic or agarose bead formats, these reagents integrate easily into existing immunoprecipitation workflows. They are suitable for isolating antibody-antigen complexes for downstream analysis by Western blotting, mass spectrometry and related proteomic techniques.

Anti-IgG VHH Beads Key Features

Recombinant nanobody technology for IgG capture.
High specificity with low background binding.
Ready-to-use magnetic and agarose bead formats.
Excellent reproducibility between experiments.
Suitable for immunoprecipitation and co-immunoprecipitation.
Compatible with downstream proteomic analysis.
Reliable recombinant manufacturing.
Reduced variability compared with traditional capture resins.
Simplified laboratory workflows.
Supported by Mason Technology’s technical team.

Reliable antibody capture is fundamental to successful immunoprecipitation experiments. Anti-IgG VHH Beads provide researchers with a modern alternative to conventional capture technologies, delivering cleaner protein isolation and improved consistency while reducing assay variability. Their recombinant design supports dependable performance across a wide range of molecular biology and proteomics applications.

Mason Technology supplies ChromoTek Anti-IgG VHH Beads throughout Ireland, helping laboratories access innovative nanobody technologies backed by expert local support and technical advice.

Finding the right products for your research can be overwhelming. Proteintech’s new AI powered search tool, ‘Able’, makes the process easier and faster.

NEED EXPERT ADVICE?

Quick View Enquire Now

Nano-Secondary® Reagents

Nano-Secondary® Reagents from ChromoTek, available through Mason Technology, provide an innovative alternative to conventional secondary antibodies f...

More About Nano-Secondary® Reagents

Expand Close

Nano-Secondary® Reagents

Nano-Secondary® Reagents from ChromoTek, available through Mason Technology, provide an innovative alternative to conventional secondary antibodies for fluorescence microscopy, Western blotting and other immunodetection applications. Based on recombinant VHH nanobody technology, Nano-Secondary® Reagents deliver exceptional specificity, reduced background staining and significantly improved imaging resolution. Their small molecular size allows fluorophores or detection labels to be positioned much closer to the target protein, making them particularly valuable for advanced microscopy techniques.

Unlike traditional IgG secondary antibodies, Nano-Secondary® Reagents are approximately one tenth of the size, reducing steric hindrance and improving tissue penetration. This enables more accurate localisation of target proteins while minimising non-specific binding. Recombinant production also ensures excellent batch-to-batch consistency, helping researchers generate reproducible results across long-term studies.

Nano-Secondary® Reagents are compatible with commonly used primary antibodies from a range of host species and are available with different detection formats to suit fluorescence imaging, Western blotting and other protein detection workflows. Their compact structure makes them especially beneficial for super-resolution microscopy where minimising the distance between fluorophore and target protein is essential.

Nano-Secondary® Reagents Key Features

Recombinant VHH nanobody based secondary reagents.
Significantly smaller than conventional secondary antibodies.
Improved imaging resolution and target localisation.
Reduced background and non-specific staining.
Excellent tissue penetration.
Suitable for fluorescence microscopy and Western blotting.
Ideal for super-resolution imaging applications.
Consistent recombinant production.
Reliable batch-to-batch performance.
Expert technical support from Mason Technology.

High quality secondary detection reagents are essential for generating reliable imaging data. Nano-Secondary® Reagents provide researchers with cleaner staining, enhanced resolution and improved experimental reproducibility, making them a valuable addition to modern molecular and cellular biology workflows. Their innovative nanobody design supports demanding research applications where accuracy and sensitivity are critical.

Mason Technology supplies the complete ChromoTek Nano-Secondary® portfolio throughout Ireland, helping researchers select the most appropriate reagents for advanced imaging and protein detection applications.

Finding the right products for your research can be overwhelming. Proteintech’s new AI powered search tool, ‘Able’, makes the process easier and faster.

NEED EXPERT ADVICE?

Quick View Enquire Now

Chromobodies®

Chromobodies® from ChromoTek, available through Mason Technology, enable researchers to visualise proteins within living cells in real time without d...

More About Chromobodies®

Expand Close

Chromobodies®

Chromobodies® from ChromoTek, available through Mason Technology, enable researchers to visualise proteins within living cells in real time without disrupting normal cellular function. Built using recombinant nanobody technology fused to fluorescent proteins, Chromobodies® combine exceptional target specificity with live cell compatibility, allowing dynamic biological processes to be monitored as they occur. This innovative approach provides valuable insights into protein localisation, trafficking and cellular responses that cannot be observed using fixed cell imaging alone.

Unlike conventional antibody staining, Chromobodies® are genetically encoded intracellular probes that continuously recognise specific endogenous proteins or protein tags within living cells. Their small size minimises interference with normal protein function while delivering highly specific fluorescence signals suitable for long-term imaging studies.

Chromobodies® are widely used in cell biology, cancer research, neuroscience and drug discovery, supporting investigations into cytoskeletal dynamics, signalling pathways, cell division and protein transport. Their ability to monitor cellular events in real time provides researchers with a powerful tool for studying biological mechanisms under physiologically relevant conditions.

Chromobodies® Key Features

Recombinant nanobody technology for live cell imaging.
Real time visualisation of intracellular proteins.
Minimal disruption to normal cellular function.
High specificity and low background fluorescence.
Suitable for long-term imaging experiments.
Supports cell biology, oncology and neuroscience research.
Compatible with fluorescence microscopy platforms.
Reliable recombinant production.
Excellent experimental reproducibility.
Supported by Mason Technology’s technical specialists.

Understanding dynamic cellular processes requires tools that allow continuous observation without altering normal cell behaviour. Chromobodies® provide researchers with an advanced imaging solution that delivers real time insights into protein function, localisation and movement. Their innovative design supports cutting-edge research across numerous life science disciplines while improving confidence in experimental findings.

Mason Technology supplies ChromoTek Chromobodies® throughout Ireland, combining access to innovative live cell imaging technology with responsive local technical support and application expertise.

Finding the right products for your research can be overwhelming. Proteintech’s new AI powered search tool, ‘Able’, makes the process easier and faster.

NEED EXPERT ADVICE?

Quick View Enquire Now

Nano-Caps®

Nano-Caps® from ChromoTek, available through Mason Technology, provide researchers with an efficient nanobody based solution for affinity purificatio...

More About Nano-Caps®

Expand Close

Nano-Caps®

Nano-Caps® from ChromoTek, available through Mason Technology, provide researchers with an efficient nanobody based solution for affinity purification of tagged recombinant proteins. Designed to deliver high specificity and reproducibility, Nano-Caps® simplify protein purification workflows while maintaining excellent recovery and purity. Their recombinant nanobody technology enables reliable capture of target proteins, supporting downstream biochemical, structural and functional studies.

Traditional affinity purification methods can be affected by variable binding performance and increased background contamination. Nano-Caps® overcome these challenges by using recombinant single-domain nanobodies that bind target protein tags with exceptional affinity and precision. Their compact structure improves access to target epitopes while reducing non-specific interactions, resulting in cleaner protein preparations and more reliable experimental outcomes.

Nano-Caps® are suitable for a variety of protein purification workflows and integrate easily into existing laboratory protocols. Their high binding efficiency and robust performance make them valuable tools for structural biology, enzymology, protein interaction studies and recombinant protein production.

Nano-Caps® Key Features

Recombinant nanobody based affinity purification.
High specificity for tagged recombinant proteins.
Excellent protein recovery and purity.
Reduced non-specific protein binding.
Reliable recombinant manufacturing.
Consistent batch-to-batch performance.
Suitable for structural biology and proteomics.
Compatible with standard purification workflows.
Simplifies recombinant protein isolation.
Supported by Mason Technology.

Efficient protein purification is fundamental to successful downstream analysis. Nano-Caps® provide researchers with dependable affinity capture technology that improves protein purity while reducing workflow complexity. Their recombinant nanobody design delivers reproducible performance, making them an excellent choice for laboratories seeking high quality protein purification solutions.

As ChromoTek’s trusted supplier in Ireland, Mason Technology provides access to the complete Nano-Caps® portfolio together with expert product advice and technical support to help laboratories optimise protein purification workflows.

Finding the right products for your research can be overwhelming. Proteintech’s new AI powered search tool, ‘Able’, makes the process easier and faster.

NEED EXPERT ADVICE?

Quick View Enquire Now

Nano-CaptureLigands®

Nano-CaptureLigands® from ChromoTek, available through Mason Technology, provide researchers with a highly efficient solution for affinity purificati...

More About Nano-CaptureLigands®

Expand Close

Nano-CaptureLigands®

Nano-CaptureLigands® from ChromoTek, available through Mason Technology, provide researchers with a highly efficient solution for affinity purification of recombinant proteins and biologics. Developed using recombinant nanobody technology, Nano-CaptureLigands® combine exceptional binding specificity with excellent stability, allowing laboratories to purify proteins with high yield and reproducibility. Their robust performance makes them an ideal choice for research, process development and biopharmaceutical manufacturing workflows where reliable protein capture is essential.

Unlike conventional affinity ligands, Nano-CaptureLigands® are engineered from recombinant single domain antibodies that deliver consistent performance while reducing non specific interactions. Their compact molecular structure enables efficient access to target proteins and supports high binding capacity across a wide range of purification conditions. Recombinant production also ensures excellent batch to batch consistency, providing researchers and manufacturers with dependable reagents for critical purification processes.

Nano-CaptureLigands® are suitable for purification of recombinant proteins, antibody fragments and other biologics used in life science research and therapeutic development. Their high affinity and chemical stability enable efficient purification while maintaining target protein integrity, helping laboratories improve productivity and downstream analytical performance.

Nano-CaptureLigands® Key Features

Recombinant nanobody based affinity ligands.
High specificity for recombinant protein purification.
Excellent binding capacity and protein recovery.
Reduced non specific binding.
Stable under demanding purification conditions.
Consistent recombinant manufacturing.
Reliable batch to batch reproducibility.
Suitable for research and bioprocess development.
Supports purification of recombinant proteins and biologics.
Expert technical support from Mason Technology.

Reliable affinity purification is fundamental to producing high quality recombinant proteins for research and therapeutic development. Nano-CaptureLigands® provide a modern alternative to conventional purification technologies by combining recombinant nanobody engineering with exceptional binding performance and reproducibility. Their ability to deliver efficient protein capture while maintaining sample quality makes them an excellent solution for laboratories seeking dependable purification workflows.

As Proteintech’s trusted partner in Ireland, Mason Technology supplies the complete ChromoTek Nano-CaptureLigands® portfolio together with responsive technical support and expert product guidance. Our experienced Life Sciences team can help identify the most appropriate purification solution for your laboratory, ensuring reliable performance from discovery research through to advanced bioprocess applications.

Finding the right products for your research can be overwhelming. Proteintech’s new AI powered search tool, ‘Able’, makes the process easier and faster.

NEED EXPERT ADVICE?

Quick View Enquire Now

Spot Tag® Capture & Detection System

The Spot Tag® Capture & Detection System from ChromoTek, available through Mason Technology, provides researchers with a versatile and highly sen...

More About Spot Tag® Capture & Detection System

Expand Close

Spot Tag® Capture & Detection System

The Spot Tag® Capture & Detection System from ChromoTek, available through Mason Technology, provides researchers with a versatile and highly sensitive solution for recombinant protein detection, imaging and purification. Built around the compact 12 amino acid Spot Tag® peptide and a highly specific recombinant nanobody, the system enables reliable protein analysis while minimising interference with protein structure and biological function. Its small tag size makes it particularly valuable for applications where larger affinity tags may affect protein expression, localisation or activity.

The Spot Tag® System combines efficient protein capture with sensitive detection across a broad range of molecular biology techniques. Researchers can use the system for immunofluorescence, Western blotting, immunoprecipitation and affinity purification, all while benefiting from the exceptional specificity and reproducibility associated with ChromoTek’s recombinant nanobody technology. The minimal size of the Spot Tag® also reduces steric hindrance, allowing proteins to behave more naturally within experimental systems.

Designed for flexibility, the Spot Tag® platform supports a wide variety of recombinant protein workflows, from routine laboratory experiments to advanced cell biology and structural biology research. Recombinant manufacturing ensures excellent batch to batch consistency, enabling laboratories to generate reproducible data with confidence.

The Spot Tag® Capture & Detection System provides researchers with a flexible alternative to traditional affinity tags by combining a minimal peptide tag with highly specific recombinant nanobody technology. This innovative approach enables accurate protein detection while preserving natural protein behaviour, making it particularly valuable for demanding molecular and cellular biology applications.

Mason Technology supplies the complete ChromoTek Spot Tag® portfolio throughout Ireland, providing expert product advice, technical support and responsive customer service. Whether you are establishing a new recombinant protein workflow or optimising an existing protocol, our experienced Life Sciences team can help you select the most appropriate Spot Tag® reagents for your research.

Finding the right products for your research can be overwhelming. Proteintech’s new AI powered search tool, ‘Able’, makes the process easier and faster.

NEED EXPERT ADVICE?

Nanobody Reagents

ChromoTek® Nanobody Based Reagents Key Features

FEATURED PRODUCTS

Nano-Traps®

Nano-Traps® Key Features

Primary VHH Nanobodies

Primary VHH Nanobodies Key Features

Anti-IgG VHH Beads for Immunoprecipitation

Anti-IgG VHH Beads Key Features

Nano-Secondary® Reagents

Nano-Secondary® Reagents Key Features

Chromobodies®

Chromobodies® Key Features

Nano-Caps®

Nano-Caps® Key Features

Nano-CaptureLigands®

Nano-CaptureLigands® Key Features

Spot Tag® Capture & Detection System

Spot Tag® Capture & Detection System Key Features