AXIMA Confidence overview
- The Shimadzu AXIMA Confidence has powerful MALDI-TOF performance for reliable mass information and MS/MS derived structural detail.
- Linear mode allows the interrogation of high molecular weight samples, whilst reflectron mode, incorporating the patented curved-field reflectron (CFR), provides the high resolution and mass accuracy necessary for successful proteomics and life science experiments.
- High sensitivity system using a variable repetition rate 50 Hz N2 laser and a variety of target formats to meet all sample throughput requirements.
- An affordable robust option for all laboratories requiring routine manual or automated analysis of a wide variety of sample classes.
- Excellent sensitivity is achieved using near-axis laser irradiation and advanced ion optics for enhanced ion transmission.
- MS/MS may be easily performed using a seamless approach – ions of interest can be isolated using a precursor ion selection device, incorporated as standard, and data-rich fragment ion spectra quickly and simply acquired.The newly improved curved field reflectron design augments the low mass fragment region providing useful additional information.
Shimadzu AXIMA Confidence features and benefits
Key Performance Features
- Near-axis laser irradiation with a 50Hz variable repetition rate N2 laser
- Patented improved curved field reflectron
- Mass range 1-500kDa in linear mode; 1-80kDa in reflectron mode
- Mass resolution 5000 FWHM (ACTH 18-39) in linear mode; 15000 FWHM (ACTH 7-38) in reflectron mode
- Sensitivity 500 amol (Glu-fibrinopeptide) in reflectron mode
- Mass accuracy <10ppm in reflectron mode with internal calibration
- Precursor ion resolution >200 FWHM
- Seamless MS/MS utilising PSD
- Flexible target formats – ranging from 48 well microscope slide format targets to 384 well microtitre plate targets
Key Benefits
- Proteomics experiments
- LC MALDI
- Polymer analysis
- Tissue imaging/biomarker discovery
- Oligonucleotide/primer analysis
- Full integration with robotic sample preparation devices such as the Accuspot and ChIP for a variety of applications