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MALDI-7090 | Multi-user high-performance MALDI TOF-TOF Mass Spectrometer


MALDI-7090 | Multi-user high-performance MALDI TOF-TOF Mass Spectrometer

The Shimadzu MALDI-7090 is targeted for proteomics and tissue imaging. It combines Shimadzu’s extensive MALDI TOF-TOF mass spectrometry expertise with novel patented technology to provide ultimate performance in identification and structural characterization of biomolecules.


MALDI-7090 overview

  • Market leading MS/MS resolution
  • Proprietary solid state UV laser technology
  • Ultra Fast acquisition speed in MS and MS/MS
  • Integrated 10 plate loader
  • Newly designed MALDI Solutions™ software


Multi-user high-performance MALDI TOF Mass Spectrometer application areas

MALDI Solutions™ is the completely new software interface for the MALDI-7090 MALDI TOF-TOF mass spectrometer. Providing a powerful range of tools for method development, acquisition, data processing and interpretation, MALDI Solutions has been designed for ease of use and reliability. Each function within the MALDI Solutions suite is targeted to a particular application such as LC, MALDI, MALDI imaging or manual control, creating a simple and versatile application-centric platform.


MALDI-7090 features

  • MultiPlex: MultiPlex maximizes the efficient use of the MALDI-7090 through the combination of the integrated 10 plate loader, the 2 kHz ultra fast UV laser and the MALDI Solutions™ multi-user environment software.
  • A source design like no other: The MALDI-7090 includes a number of proprietary features to improve sensitivity and productivity.
    • Wide Bore ion Optics: Consisting of unique wide-bore extraction optics, the MALDI-7090 ion optics are designed to maximize ion transmission and minimize source contamination over time.
    • Ultra fast Laser: Shimadzu’s proprietary solid-state UV laser, designed specifically for the MALDI-7090, delivers true 2kHz acquisition speed in all modes. The added benefits of variable beam focus and long lifetime maximize reliability and broad-range applicability.
    • HD sample viewing: It incorporates the latest state-of-the -art camera technology to deliver high-quality full HD color images of the sample with 10µm viewing resolution, software-controlled variable focus and long-life LED illumination.
    • TrueClean™: Optimal performance of the MALDI-7090 source is maintained using TrueClean – a novel and fully automated source cleaning process. TrueClean cleans the source electrodes by redirecting the UV laser onto their surface and desorbing any contaminant material. This method is highly efficient and does not require source removal or venting.
  • High-resolution ion gate: It is equipped with a dual wire-grid high resolution ion gate. Compounds of similar nominal mass may produce MS/MS spectra that contain fragment ions from several precursors if not gated correctly. However, the high-resolution ion gate in the MALDI-7090 allows the individual gating of species close in nominal mass thus producing distinct fragment ion spectra.
  • Axial Spatial Distribution Focusing – ASDF: ASDF is a Shimadzu patented technology that enables unparalleled resolution in MS/MS acquisitions. Through correction of the axial spatial distribution of the ions generated, the mass resolution is significantly increased and becomes essentially independent of the laser power used to ionize the sample.
  • High- and low-energy fragmentation:
    • High-energy CID: MS/MS fragmentation in the MALDI-7090 is true high-energy CID (HE-CID).
    • Low-energy fragmentation (metastable decay): It can also be used in low-energy fragmentation mode without collision gas. Here the fragmentation relies on spontaneous metastable decay of the precursor and exhibits low-energy type ions.
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