GCMS
Gas chromatography-mass spectrometry (GCMS) is an analytical technique that combines the separation capabilities of gas-chromatography (GC) with the detection power of mass spectrometry (MS). This method is highly effective for identifying and quantifying volatile compounds within complex mixtures. Gas chromatography separates the components based on their volatility, while mass spectrometry provides detailed molecular information by fragmenting the compounds and analyzing their mass-to-charge ratios. The synergy of these two techniques allows for precise and comprehensive analysis, making GCMS an invaluable tool in fields such as environmental monitoring, pharmaceuticals, and forensic science.
Shimadzu is one of the world’s leading manufacturers of gas chromatograph mass spectrometers. Shimadzu’s GC-MS instruments boast ultra-high sensitivity and high efficiency, and are designed to maximize lab productivity while minimizing environmental impact. Their state-of-the-art GC-MS systems are equipped with numerous advanced features. The systems boast high-resolution mass spectrometry, fast scanning capabilities, and robust data analysis software, ensuring precise and efficient results. We also offer a variety of columns, detectors, and sample preparation tools to enhance your analytical workflows.
We offer a comprehensive GC-MS product lineup for every application. From our triple quadrupole GC-MS/MS (GCMS-TQ8040 NX and GCMS-TQ8050 NX) to our single quadrupole GC-MS (GCMS-QP2020 NX). Along with a variety of accessories and software to enhance your GC/MS analysis.
FEATURED PRODUCTS
The Shimadzu triple-quad GCMS-TQ8050 NX is capable of performing unprecedented quantitative GC-MS/MS analyses of ultra-trace amounts, down to the femt...
More About GCMS-TQ8050 NX | Triple Quadrupole GC-MS
GCMS-TQ8050 NX | Triple Quadrupole GC-MS 
The Shimadzu triple-quad GCMS-TQ8050 NX is capable of performing unprecedented quantitative GC-MS/MS analyses of ultra-trace amounts, down to the femtogram level. Equipped with a new, highly efficient detector and three forms of noise-reduction technologies, the GCMS-TQ8050 NX has never been more important in industries such as food safety, cannabis testing, forensics, and more.
GCMS-TQ8050 NX Triple Quadrupole GC-MS overview
Enhanced sensitivity enables ultra-trace level analysis
To maximize the benefits of the Off-Axis Ion Optics, the system features three noise-reduction technologies and a detector with improved amplification performance. Due to these state-of-the-art technologies, the system can reliably detect ultra-trace femtogram-level quantities of ions. The resulting exceptional analytical sensitivity and robustness increase the value of solutions and open the door to new applications.
- High-Efficiency Detector: The GCMS-TQ8050 NX detects peaks more reliably than the GCMS-TQ8040 NX, even for substances with fewer ions reaching the detector. That means it can reliably analyze femtogram-level concentrations with fewer ions.
Simplified user maintenance allows operators to change parts quickly
- Active-Time Management™ That Accurately Determines Operation Time: The mass spectrometer has to be operated in a vacuum condition, the startup and stopping of the system takes time depending on the condition. Determining this can be a challenge. Since the amount of time that the system takes when starting up or stopping is displayed in real time, it is easy to accurately determine when maintenance of the ion source or analysis is possible. Moreover, tasks that until now needed to be performed by the user, such as leak checks upon system startup and auto tuning, are now performed automatically.
- Time Management during Injection Port Maintenance: The Easy sTop function, used to safely maintain the sample injection port without releasing the vacuum, displays the remaining time (coolingdown time) when the septum or the insert can be replaced in real time. Maintenance time can be minimized by understanding the accurate remaining time. Furthermore, by using a ClickTek nut on the top of the sample injection port, the port can be opened or closed without tools, by simply using fingers to twist a lever. That enables faster and easier insert replacement than ever before.
- Time Management for Continuous Analysis: By displaying the time required for continuous analysis in real time, the time when the current continuous analysis will finish can be accurately confirmed. This increases the instrument operating time (active time) by reducing standby time required during continuous analysis or while switching between different users. In addition, because this function makes it easier to schedule the timing for analysis preparations, such as sample preparation and pretreatment, based on the finish time of the previous analysis, it enables analytical processes to be performed more efficiently, which can help improve work-life balance.
Reduces maintenance frequency and long-term operational costs
In addition to ultra-high sensitivity, the GCMS-TQ8050 NX also offers high robustness. The contamination-resistant ion source and the new detector with over five times longer service life ensure that analysis can be performed reliably for a long time. With the ultra-high-sensitivity performance of the GCMS-TQ8050 NX, injection volumes can be reduced even further than before. The service life of inserts, columns, and other consumables can also be extended to reduce maintenance frequency and costs.
- Highly Sensitive and Stable Ion Source: The effect of the filament’s electric potential on the ion source is reduced by placing more distance between the filament and ion source box. In addition, a shield blocks out radiant heat generated from the filament to ensure the ion source box temperature remains uniform. Since this prevents any active spots within the ion source, it provides higher sensitivity for analysis. (Patent: US7939810)
- High-Performance Quadrupole Mass Filter: The high-accuracy mass filter with pre-rods and patented electric field control technology achieves high-accuracy mass separation performance. Also, the pre-rods minimize quadrupole contamination and eliminate the need for quadrupole maintenance.
- Long-Life Detector: Exhaustive efforts to reduce detector loads during analysis resulted in a significantly longer detector service life. Consequently, the instrument needs to be maintained much less frequently, which results in greater uptime.
The Shimadzu triple-quad GCMS-TQ8040 NX features smart technologies to boost the efficiency of routine analytical work. For example, Smart MRM provide...
More About GCMS-TQ8040 NX | Triple Quadrupole GC-MS
GCMS-TQ8040 NX | Triple Quadrupole GC-MS
The Shimadzu triple-quad GCMS-TQ8040 NX features smart technologies to boost the efficiency of routine analytical work. For example, Smart MRM provides fully-automated MRM method development. It automatically determines all optimum transitions and collision energies, seamlessly incorporating them into the Smart Database Series. With features like this, the GCMS-TQ8040 NX GC-MS/MS is so smart it almost runs itself! Perfect for applications in fields such as environmental monitoring and food science.
GCMS-TQ8040 NX overview
Simplified user maintenance allows operators to change parts quickly
- Active-Time Management™ That Accurately Determines Operation Time: The mass spectrometer has to be operated in a vacuum condition, the startup and stopping of the system takes time depending on the condition. Determining this can be a challenge. Since the amount of time that the system takes when starting up or stopping is displayed in real time, it is easy to accurately determine when maintenance of the ion source or analysis is possible. Moreover, tasks that until now needed to be performed by the user, such as leak checks upon system startup and auto tuning, are now performed automatically.
- Time Management during Injection Port Maintenance: The Easy sTop function, used to safely maintain the sample injection port without releasing the vacuum, displays the remaining time (coolingdown time) when the septum or the insert can be replaced in real time. Maintenance time can be minimized by understanding the accurate remaining time. Furthermore, by using a ClickTek nut on the top of the sample injection port, the port can be opened or closed without tools, by simply using fingers to twist a lever. That enables faster and easier insert replacement than ever before.
- Time Management for Continuous Analysis: By displaying the time required for continuous analysis in real time, the time when the current continuous analysis will finish can be accurately confirmed. This increases the instrument operating time (active time) by reducing standby time required during continuous analysis or while switching between different users. In addition, because this function makes it easier to schedule the timing for analysis preparations, such as sample preparation and pretreatment, based on the finish time of the previous analysis, it enables analytical processes to be performed more efficiently, which can help improve work-life balance.
Smart Database Series provides automated method development
- Smart Database: The Shimadzu “Smart Database” is a database file for creating the method files using “Smart MRM” function. In addition to compound information and transitions, retention index can be registered in the database file. Method creation can be proceeded without calculating the retention time by analyzing the standard samples when using the Automatic Adjustment Retention Time (AART) function. In addition to MRM information, Scan and SIM ion information, mass spectra and calibration curve information from the internal standard method can also be registered in the database file. This allows users to create their own database easily.
Smart MRM sets method to maximize sensitivity
- Smart MRM: Smart MRM makes method development quick and easy. Whether starting from scratch to optimize transitions and collision energies for new compounds, or starting from an MRM database of known target analytes to build a custom MRM method, Smart MRM takes the stress and difficulty out of method development.
The Shimadzu single quadrupole GCMS-QP2020 NX gas chromatograph-mass spectrometer (GC-MS) not only boasts the best performance in its class, but also ...
More About GCMS-QP2020 NX | Single Quadrupole GC-MS
GCMS-QP2020 NX | Single Quadrupole GC-MS
The Shimadzu single quadrupole GCMS-QP2020 NX gas chromatograph-mass spectrometer (GC-MS) not only boasts the best performance in its class, but also the highest efficiency. This new high-end single-quad GCMS excels in both ease-of-use and robustness. The role of high-performance analytical instruments is expanding in areas as diverse as environmental pollution monitoring, forensics and material science. Whatever your field, the efficient and reliable GCMS-QP2020 NX is tailored to meet the needs of your laboratory.
GCMS-QP2020 NX overview
Smart Performance
- Provides higher sensitivity and reduces operational costs: A large-capacity differential exhaust turbomolecular pump and a high-performance flow controller ensure that the utmost in sensitivity is obtained under all conditions used for GC. This sensitivity combined with high-speed analysis capabilities helps maximize laboratory efficiency by reducing analysis times. In addition, the system can be safely operated using carrier gases other than helium, such as hydrogen or nitrogen, thereby reducing operating costs.
- Ion Source Featuring High Sensitivity and Long-Term Stability: The filament and the ion source box have been separated, which reduces the impact of the filament potential on the interior of the ion source. In addition, a shield is provided to block radiant heat generated by the filament, achieving a uniform temperature inside the ion source box. Thus, active spots inside the ion source are not prone to occur, enabling high-sensitivity analysis with long-term stability. (Patent: US7939810)
- New Flow Controller Achieves Exceptional Reproducibility: A new flow controller (AFC) with a CPU uses various control methods to control carrier gas flow to a constant flow speed, flowrate, or pressure. It can also accurately trace the analytical conditions already being used. The split line filter can be replaced without any tools. Internal contamination can be confirmed visually, ensuring filters are replaced at the proper time.
- Large-Capacity Differential Exhaust System: Through adoption of a new type of turbomolecular pump with increased exhaust efficiency, the system’s performance is greatly improved when using hydrogen or nitrogen, in addition to helium, as the carrier gas. Moreover, a differential exhaust method is used to create a vacuum separately for the ion source and the quadrupole. As a result, an optimal MS state can be realized regardless of the conditions imposed by the carrier gas used.
Smart Operation
- Dramatic improvement in the efficiency of multicomponent simultaneous analysis: The efficiency of multi-component simultaneous analysis is dramatically improved thanks to Smart SIM™, which simplifies and automates the method creation, and LabSolutions Insight™ software, which greatly reduces the time needed for analyzing data. In addition, databases specialized for specific fields are provided, so regardless of the field in which quantitative analysis is to be performed, highly reliable data can be obtained as the result of the optimized analytical conditions.
- More Convenient Multicomponent Analysis Achieved by Smart SIM: The Smart SIM automatic method creation function automatically configures the SIM program to suit the retention times. Even in cases where there are a number of compounds and they are apportioned to multiple methods, the methods can be integrated while maintaining the sensitivity as is. This significantly reduces the number of analysis cycles and the measurement time, improving productivity.
Smart Data Management
- Easily obtains all the information required for qualitative analysis: With GC/MS, which has significant qualitative capabilities, a wealth of fragment information is obtained, so it is used as a means of identifying unknown compounds. A mass spectral library is generally used as a means of compound identification. However, experience with compound identification is required if the compound is not registered in the mass spectral library, or there are a number of compounds with similar structures. With the GCMS-QP2020 NX, in addition to the mass spectrum, three kinds of value-added compound information are used in combination to support high-accuracy qualitative analysis.
- Databases Containing High Value-Added Retention Indices: Databases are available with retention indices specific to a variety of application fields, including foods, chemistry, fragrances, forensics, and metabolite component analysis. In addition to mass spectra, searches are performed in combination with retention indices, which are very highly compound specific, so isomers and compounds with similar structures are accurately identified.
- Smart EI/CI Ion Source Easily Switches Between EI and CI Methods: The Smart EI/CI ion source has been developed in order to acquire CI data without switching the ion source, and without losing the sensitivity of EI, which is most commonly used. Even when it is difficult to perform identification with the EI mode using the mass spectral library, molecular weight information can be obtained from CI data, thus helping in the estimation of unknown compounds.
The Shimadzu GCMS-QP2010 SE is a single quadrupole gas chromatograph-mass spectrometer offering stable and cost-effective analysis for challenging com...
More About GCMS-QP2010 SE | Single Quadrupole GC-MS
GCMS-QP2010 SE | Single Quadrupole GC-MS
The Shimadzu GCMS-QP2010 SE is a single quadrupole gas chromatograph-mass spectrometer offering stable and cost-effective analysis for challenging compounds. A high-performance quadrupole mass filter ensures high sensitivity in both quantitative and qualitative analysis. The GCSMS-QP2010 SE is compatible with multiple sample introduction methods to enable a greater range of applications.
GCMS-QP2010 SE features
- A front-opening ion source chamber minimizes downtime by allowing maintenance to be performed quickly from the front of the instrument
- Routine analyses are fully automated using a range of sample introduction techniques, including large-volume and temperature-programmable injections, direct insertion probe, headspace, purge-and-trap, and others
- Robust single turbomolecular pump system that allows for twin-line configurations, helping your lab to maximize efficiency
- Ecology mode reduces costs associated with power and carrier gas consumption when the instrument is in standby
GCMS-QP2010 SE overview
Easy maintenance reduces downtime
- Design Offers the Ultimate in Ease of Use: The GCMS-QP2010 SE incorporates a front-opening chamber in a design that is both visually pleasing and practical, allowing maintenance to be performed with ease from the front of the instrument. “MSNAVIGATOR,” which supports maintenance, has been improved to help the user perform instrument maintenance.
Superior technology achieves high sensitivity and stability
-
Stable Mass Spectra: The ion optics are optimized by employing a high-performance quadrupole mass filter and Shimadzu’s proprietary Optdesign simulation program to provide high-quality mass spectra. Fully-automated MS tuning enables anyone to optimize parameters easily and consistently. This helps ensure that stable mass spectra can always be obtained.
High-Performance Quadrupole Mass Filter: Shimadzu’s patented technology for mass scanning produces ideal mass filter characteristics (Patent: US5227629). This system features an easily removable pre-rod and lens system that allows the user to quickly perform cleaning and maintenance. Less downtime means greater productivity.
GC-MS System Based on New Environmentally Friendly Concepts
- An “Ecology mode” Saves Power Consumption and Reduces Instrument Running Costs:By activating the new Ecology mode feature whenever the system is in between analyses or after finishing a batch of analyses, the GCMS-QP2010 SE will use about 60 % less carrier gas and 40 % less power than previous models. Given typical operating conditions,* this reduces helium gas consumption by about 2 cylinders (with a capacity of 7 m3) per year, reducing laboratory operating costs.
*Using standard analytical conditions. - Reduction of Power Consumption in Standby Mode:When Ecology mode is entered, unnecessary power consumption by the GC, MS, and PC is automatically eliminated. The consumption of carrier gas is also automatically reduced. Furthermore, Ecology mode can be entered automatically after a batch run, allowing the lab to realize running cost savings on a nightly basis.
The next-generation Shimadzu GCMS-QP2050 gas chromatograph mass spectrometer, with its accumulation of impressive Shimadzu technology, will lead the w...
More About GCMS-QP2050 | Single Quadrupole GC-MS
GCMS-QP2050 | Single Quadrupole GC-MS
The next-generation Shimadzu GCMS-QP2050 gas chromatograph mass spectrometer, with its accumulation of impressive Shimadzu technology, will lead the way forward. New value is provided by hardware boasting astounding reliability and stability, and easy-to-operate software equipped with superior automated technology.
GCMS-QP2050 Overview
Minimum Maintenance, Maximum Progress
- Contamination-Resistant Ion Optical System: A contamination-resistant ion optical system in the GCMS-QP2050 keeps the frequency of maintenance to a minimum while also enabling highly reliable measurements to be performed for an extended period.
- Long-Life Filament with 1/5th the Conventional Replacement Frequency: The newly developed long-life filament has an operating life at least five times longer than conventional filaments. There are no concerns about re-analysis or downtime due to sudden filament burnout.
- High Durability in Consecutive Analyses: The GCMS-QP2050, which boasts incomparable robustness, achieves extremely stable measurements, even during consecutive analyses of VOCs in water, by eliminating the effects of elution of the column bleed to the utmost limit.
Simple Operation, Confident Results
- Ion Source Maintenance Takes Just One Minute: With the DuraEase ion source, the conventional ion source structure has been completely revised, in pursuit of more convenient maintenance. The ion source is disposable and no cleaning is required, so maintenance is finished in just one minute.
- One-Touch GC Inlet Maintenance: The instrument is equipped as standard with a ClickTek™ nut, enabling the GC injection port to be attached or detached simply by manipulating a lever by hand, without tools.
- Easy Startup and Shutdown from the Touch Panel: The vacuum system can be turned ON/OFF and Easy sTop* can be performed from the GC touch panel. Operations from a personal computer are not required, so maintenance of the GC injection port, column, and ion source can proceed with ease. * This function guides the user through the replacement of the GC injection port septum and glass insert without turning OFF the vacuum system.
One Instrument, Infinite Possibilities
- Minimizing the Usage of Helium Gas: Using the included carrier gas save function makes it possible to reduce the amount of carrier gas used during analysis. Additionally, with the optional gas selector, the carrier gas can be switched from helium to nitrogen except during analysis, thereby minimizing helium gas consumption during standby.
- Reliable Operation with Alternative Carrier Gases: Hydrogen and nitrogen, which cost less and are easier to acquire, can be used as the carrier gas. With its high-performance flow controller and a design that reduces the impact of the carrier gas, the GCMS-QP2050 can perform stable measurements using either gas without modifying the instrument configuration.
- Remote System Access: The system can be operated from a personal computer or tablet on the network via a LAN connection. Additionally, analysis and instrument status can be checked while away from the laboratory.
- Energy Savings: The GCMS-QP2050 is equipped with ecology mode, which can reduce power consumption. It is also recognized as Eco-Products Plus, Shimadzu’s proprietary recognition of environmentally friendly products. In addition to limiting analysis running costs, CO2 emissions are limited, thereby contributing to a carbon-free society.