One System, Two Solutions: Advanced PFAS & Cyanotoxin Testing for Safer Water

EPA 537.1, 544 & 545 Compliant LC-MS Solution

Duration: 60 minutes
Format: On-demand
Registration: Free (registration required)

This webinar forms part of Shimadzu’s PFAS in Focus technical series and addresses the growing regulatory and analytical challenges associated with PFAS and cyanotoxin monitoring in drinking and environmental water.

Per- and polyfluoroalkyl substances (PFAS) from environmental contamination and cyanotoxins from algal blooms present significant risks to water quality and public safety. Laboratories responsible for compliance monitoring must implement validated analytical workflows aligned with recognised EPA methods.

This session introduces an advanced LC-MS system with dual analysis capability for both PFAS and cyanotoxins, supporting compliance with:

• EPA Method 537.1: Determination of Selected PFAS in Drinking Water
• Method 544: Determination of Microcystins and Nodularinand Nodularin
• EPA Method 545: Determination of Cylindrospermopsin and Anatoxin-a in Drinking Water by LC/ESI-MS/MS

The system provides a streamlined and cost-effective approach to comprehensive water quality testing, particularly for laboratories operating with limited space and resources.

What This Webinar Covers

During this 60-minute technical session, you will learn how to:

• Implement a dual-analysis LC-MS workflow for PFAS and cyanotoxin testing

• Achieve compliance with EPA Methods 537.1, 544 and 545

• Utilise automated method-switching to reduce manual intervention

• Improve laboratory efficiency while maintaining analytical sensitivity and robustness

The session concludes with an expert Q&A addressing practical implementation and laboratory considerations.

Why Dual PFAS and Cyanotoxin Analysis Matters

Operating separate analytical systems for PFAS and cyanotoxin testing can increase:

• Capital investment

• Laboratory footprint requirements

• Method validation workload

• Maintenance complexity

This webinar demonstrates how a single advanced LC-MS platform can support multiple regulated water testing workflows while improving operational efficiency.

Part of the PFAS in Focus Technical Series

PFAS in Focus is a 10-part technical webinar programme sponsored by Shimadzu, covering analytical strategies for PFAS testing across LC-MS/MS, GC-MS, high-resolution Q-TOF and combustion ion chromatography (CIC) platforms.

The series explores:

• Targeted PFAS quantification using LC-MS/MS
• Cyanotoxin testing in drinking and environmental water
• Non-targeted PFAS screening using high-resolution Q-TOF LC-MS
• Alternative PFAS detection techniques including GC-MS

This session focuses specifically on targeted PFAS and cyanotoxin workflows for regulated water testing.

Featured Instrumentation

This webinar highlights the Shimadzu LCMS-TQ series, designed for high-sensitivity quantitative PFAS and cyanotoxin analysis in drinking and environmental water.

Explore Shimadzu LC-MS systems for PFAS testing

Who Should Attend

• Environmental testing laboratories implementing PFAS analysis

• Drinking and wastewater utilities responding to regulatory requirements

• Academic researchers working in water contamination and environmental chemistry

• LC-MS users expanding into regulated PFAS testing